Induced Pluripotent Stem Cells Combo Could Yield Much-needed Models to Study Vascular Disease

Brian R. Wamhoff, Ph.D., Co-founder and Head of Innovation at HemoShear Therapeutics

A study recently published in STEM CELLS Translational Medicine shows smooth muscle and vascular endothelial cells induced from pluripotent stem cells perform similarly to their naturally evolving counterparts under conditions that mimic hardening of the arteries and other blood vessel diseases. The finding opens the door to modeling rare vascular diseases necessary for research, as well as assists in screening new drugs and developing personalized cell-based therapies.

Researchers have difficulty studying vascular diseases – those affecting the blood vessels – because of a…

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